The ophthalmic nerve is the first (V1) and smallest of the three nerve branches of the trigeminal nerve and is a purely sensory and afferent nerve branch.
Anatomy
The ophthalmic nerve originates as the most superior nerve from the trigeminal ganglion. The ophthalmic nerve then travels approximately 2.5 cm in the inferior lateral wall of the cavernous sinus and then enters the superior orbital fissure into the orbit[^1]. The ophthalmic nerve divides into the following nerve branches:
Lateral view of the neural structures in the orbit. Image adapted from Grays Anatomy.Schematic illustration of the cavernous sinus and its anatomical structures. Figure adapted from Grays Anatomy Figure 571.
Orbital nerves
Lateral view of the neural structures in the orbit. Image adapted from Grays Anatomy.
Cavernous sinus
Schematic illustration of the cavernous sinus and its anatomical structures. Figure adapted from Grays Anatomy Figure 571.