Corpus callosum

The corpus callosum is a transverse fiber connection between the two cerebral hemispheres and forms the largest part of the commissural system.

Anatomy

The corpus callosum is anatomically divided into three parts: the rostrum, genu, and splenium.

Rostrum corporis callosi

The rostrum corporis callosi is the anterior, tapering section of the corpus callosum below the genu corporis callosi. It is connected to the Commissura anteriorLamina terminalis.

Genu corporis callosi

The genu corporis callosi is the anterior part of the corpus callosum facing the two Frontal lobes, which tapers into the rostrum corporis callosi.

Splenium corporis callosi

The splenium corporis callosi describes the posterior thickened section of the corpus callosum.

Figure

Corpus callosum
Schematic illustration of the corpus callosum in a superior view. Figure adapted from Sobotta.

Imaging

Corpus callosum on MRI
Visualization of the corpus callosum and its various sections on sagittal 7 Tesla MRI using a contrast-enhanced T1-weighted sequence.

Clinical relevance

Common lesions that manifest in the corpus callosum include lymphomas, multiple sclerosis plaques, lipomas, or diffuse axonal injuries following trauma[^1].

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