Pneumocephalus

Synonyms
Pneumozephalus
ICD-11
8E7Y

Pneumocephalus refers to the presence of gas, usually air, within the neurocranium.

Causes

Pneumocephalus may occur, for example, after intracranial surgery, in the setting of an open traumatic brain injury, or with an intracranial infection.

Imaging

Intracranial air collections are best visualized on CT imaging and MRI imaging. Marked pneumocephalus with compression of the frontal lobe may appear on CT imaging as the so-called Mount Fuji sign.

CT

Mount Fuji sign on CT
Mount Fuji sign on an axial CT image.
Postoperative pneumocephalus
Axial CT imaging of postoperative pneumocephalus.
Postoperative pneumocephalus
Axial CT image of a patient with postoperative pneumocephalus.

MRI

Pneumocephalus on MRI
Axial T2-weighted MRI sequence of a patient with postoperative pneumocephalus. The air appears dark (hypointense) on this sequence, while the cerebrospinal fluid in the ventricular system appears hyperintense.

Treatment of postoperative pneumocephalus

Marked or symptomatic postoperative pneumocephalus can be treated by increasing the FiO2. Increasing the FiO2 leads to enhanced resorption of intracranial air[^2]. Administration of 100 % FiO2 can be tolerated for 24-48 hours without severe pulmonary toxicity[^3]. Tension pneumocephalus can cause severe symptoms and should be evacuated with urgency similar to that for an intracranial hemorrhage[^1].

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