Hypoglycorrhachia

The term hypoglycorrhachia is defined as a low glucose level in the cerebrospinal fluid and is frequently defined in the literature as a CSF glucose level of <40mg/dL1.

Causes of hypoglycorrhachia

Hypoglycorrhachia is usually indicative of bacterial, fungal, or tuberculous meningitis2. A case series of 89 patients showed the following differential diagnostic causes of hypoglycorrhachia3:

Cause Frequency
Bacterial meningitis 24 %
Fungal meningitis 15 %
Ischemia/ICB 13 %
Malignancy 11 %
Viral meningitis 6 %
Neurosarcoidosis 4 %
Neurosyphilis 4 %
Cerebral toxoplasmosis 3 %

References


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