DESTINY II Trial

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The Decompressive Surgery for the Treatment of Malignant Infarction of the Middle Cerebral Artery II (DESTINY II) Trial investigated the outcome of early decompressive hemicraniectomy compared with conservative treatment in patients over 61 years of age with a malignant middle cerebral artery infarction.

Results of the DESTINY 2 Trial
Original figure of the results of the DESTINY II Trial. Figure adapted from Jüttler et al. 2014. NEJM.

Authors' conclusion

Hemicraniectomy increased survival without severe disability among patients 61 years of age or older with a malignant middle-cerebral-artery infarction. The majority of survivors required assistance with most bodily needs1.

References

    1. Jüttler, Eric, et al. "Hemicraniectomy in older patients with extensive middle-cerebral-artery stroke." New England Journal of Medicine 370.12 (2014): 1091-1100. ↩ ↩

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    • Text changed: “The **De**compressive **S**urgery for the **T**reatment of Malignant **I**nfarction of the Middle Cerebral Arter**y** II (DESTINY II) Trial investigated the outcome of early [decompressive hemicraniectomy](\/lexikon\/dekompressive-hemikraniektomie) compared with conservative treatment in patients over 61 years of age with [malignant middle cerebral artery infarction](\/lexikon\/maligner-mediainfarkt).”“The **De**compressive **S**urgery for the **T**reatment of Malignant **I**nfarction of the Middle Cerebral Arter**y** II (DESTINY II) Trial investigated the outcome of early [decompressive hemicraniectomy](\/lexikon\/dekompressive-hemikraniektomie) compared with conservative treatment in patients over 61 years of age with a [malignant middle cerebral artery infarction](\/lexikon\/maligner-mediainfarkt).”

    Article created on · Alaric Steinmetz

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