BRAT

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The BRAT study (Barrow Ruptured Aneurysm Trial) was published in 20121.

BRAT Trial Flow Chart
BRAT Flow Chart

BRAT Trial Patient and Aneurysm Characteristics
BRAT Trial Patient and Aneurysm Characteristics

BRAT Trial Hunt and Hess Grade
BRAT Trial Hunt and Hess Grade

Authors' conclusion

One year after treatment, a policy of intent to treat favoring coil embolization resulted in fewer poor outcomes than clip occlusion. Although most aneurysms assigned to the coil treatment group were treated by coil embolization, a substantial number crossed over to surgical clipping. Although a policy of intent to treat favoring coil embolization resulted in fewer poor outcomes at 1 year, it remains important that high-quality surgical clipping be available as an alternative treatment modality2.

Follow-up

Three-year3, 6-year4, and 10-year5 follow-up data were published from the study.

References

    1. McDougall, Cameron G., et al. "The barrow ruptured aneurysm trial." Journal of neurosurgery 116.1 (2012): 135-144. ↩ ↩ ↩ ↩

    2. Spetzler, Robert F., et al. "The barrow ruptured aneurysm trial: 3-year results." Journal of neurosurgery 119.1 (2013): 146-157. ↩ ↩

    3. Spetzler, Robert F., et al. "The barrow ruptured aneurysm trial: 6-year results." Journal of neurosurgery 123.3 (2015): 609-617. ↩ ↩

    4. Darsaut, Tim E., and Jean Raymond. "Barrow Ruptured Aneurysm Trial 10-year results." Journal of Neurosurgery 133.4 (2020): 1276-1277. ↩ ↩

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    • Text changed: “## Authors' Conclusion {#schlussfolgerung-der-autoren} > One year after treatment, a policy of intent to treat favoring coil embolization resulted in fewer poor outcomes than clip occlusion. Although most aneurysms assigned to the coil treatment group were treated by coil embolization, a substantial number crossed over to surgical clipping. Although a policy of intent to treat favoring coil embolization resulted in fewer poor outcomes at 1 year, it remains important that high-quality surgical clipping be available as an alternative treatment modality[^1].”“## Authors' conclusion {#schlussfolgerung-der-autoren} > One year after treatment, a policy of intent to treat favoring coil embolization resulted in fewer poor outcomes than clip occlusion. Although most aneurysms assigned to the coil treatment group were treated by coil embolization, a substantial number crossed over to surgical clipping. Although a policy of intent to treat favoring coil embolization resulted in fewer poor outcomes at 1 year, it remains important that high-quality surgical clipping be available as an alternative treatment modality[^1].”
    • Text changed: “## Follow Up {#follow-up} A 3-year[^2], 6-year[^3], and 10-year[^4] follow-up was published based on the study data.”“## Follow-up {#follow-up} Three-year[^2], 6-year[^3], and 10-year[^4] follow-up data were published from the study.”

    Article created on · Alaric Steinmetz

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