Tethered cord

Tethered cord, or tethered cord syndrome (TCS), refers to a neurological disorder in which the Spinal cord is pathologically fixed and therefore subjected to chronic tension. This results in progressive neurological deficits, pain, and bladder and bowel dysfunction. The term was coined by Hoffman[^2] and later by Yamada[^1]. The decisive factor is not solely the anatomical anomaly, but rather the resulting functional impairment of the lumbosacral spinal cord.

Causes

Primary

A tethered cord can result from congenital malformations of the spinal cord, such as myelomeningocele, lipomyelomeningocele, or a spinal lipoma. Thickening of the Filum terminale or arachnoid adhesions can also lead to a tethered cord.

Secondary

Secondary causes may include, for example, a history of trauma or tumors.

Treatment

Surgical untethering

The standard treatment is surgical release of the tethering, known as untethering[^1].

Prognosis

The prognosis depends primarily on three factors:

  • Duration of symptoms

  • Extent of the neurological deficits

  • Age at diagnosis

Patients diagnosed early usually benefit substantially from untethering. Long-standing deficits, particularly severe neurogenic bladder dysfunction or pronounced muscle atrophy, often resolve only incompletely[^1].

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  • Text added: “Tethered cord or tethered cord syndrome (TCS) refers to a neurological disorder in which the spinal cord is pathologically fixed and therefore under chronic tension. The result is progressive neurological deficits, pain, and bladder and bowel dysfunction. The term was coined by Hoffman[^2] and later by Yamada[^1]. What is decisive here is not only the anatomical anomaly, but the resulting functional impairment of the lumbosacral spinal cord.”
  • Text added: “Causes”
  • Text added: “Primary”
  • Text added: “A tethered cord can result from congenital malformations of the spinal cord such as myelomeningocele, lipomyelomeningocele, or a spinal lipoma. Thickening of the filum terminale or adhesions of the arachnoid can also lead to a tethered cord.”
  • Text added: “Secondary”
  • Text added: “Secondary causes can include a previous trauma or tumors, for example.”
  • Text added: “Treatment”
  • Text added: “Surgical untethering”
  • Text added: “The standard treatment is surgical release of the tethering, which is referred to as untethering[^1].”
  • Text added: “Prognosis”
  • Text added: “The prognosis depends essentially on three factors:”
  • Text added: “Patients diagnosed early usually benefit significantly from untethering. By contrast, longstanding deficits, especially severe neurogenic bladder dysfunction or pronounced muscle atrophy, often regress only incompletely[^1].”
  • Citation added: “Yamada, Shokei, David E. Zinke, and Delmar Sanders. "Pathophysiology of “tethered cord syndrome”." Journal of neurosurgery 54.4 (1981): 494-503.”
  • Citation added: “Hoffman, Harold J., Bruce Hendrick, and Robin P. Humphreys. "The tethered spinal cord: its protean manifestations, diagnosis and surgical correction." Pediatric Neurosurgery 2.3 (1976): 145-155.”

Article created on · Alaric Steinmetz

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