S-100 Protein

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S-100 protein is a group of closely related small calcium-binding proteins (S-100a0, S-100a, and S-100b) and is found predominantly in brain cells[^2].

Neurosurgical Relevance

In patients after a Traumatic brain injury, serum levels of S-100 protein may be elevated[^3]. Serum levels of S-100 protein may also be elevated in patients with Creutzfeldt-Jakob disease[^1].

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Edit · Alaric Steinmetz · (+68 −12)
  • Text added: “S-100 protein is a group of closely related small calcium-binding proteins (S-100a0, S-100a, and S-100b) and is found predominantly in brain cells[^2].”
  • Text added: “Neurosurgical Relevance”
  • Text removed: “**References**”
  • Text removed: “[^1]: Greenberg M, ed. Handbook of Neurosurgery. 9th Edition. Thieme; 2019. [^2]: Donato, Rosario. "S-100 proteins." Cell calcium 7.3 (1986): 123-145.”
  • Text changed: “The S-100 protein is a group of very similar small calcium-binding proteins (S-100a0, S-100a, and S-100b) and is found predominantly in cells in the brain[^2]. In patients after a [traumatic brain injury](\/lexikon\/schaedelhirntrauma-sht), serum levels of S-100 protein may be elevated. Serum levels of S-100 protein may also be elevated in patients with Creutzfeldt-Jakob disease[^1].”“In patients after a Traumatic brain injury , serum levels of S-100 protein may be elevated[^3]. Serum levels of S-100 protein may also be elevated in patients with Creutzfeldt-Jakob disease[^1].”
  • Citation added: “Donato, Rosario. "S-100 proteins." Cell calcium 7.3 (1986): 123-145.”
  • Citation added: “Martens, Patrick, Andreas Raabe, and Per Johnsson. "Serum S-100 and neuron-specific enolase for prediction of regaining consciousness after global cerebral ischemia." Stroke 29.11 (1998): 2363-2366.”
  • Citation removed: “Greenberg M, ed. Handbook of Neurosurgery. 9th Edition. Thieme; 2019.”
  • Citation removed: “Donato, Rosario. "S-100 proteins." Cell calcium 7.3 (1986) 123-145.”
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