Parinaud syndrome

Synonyms
Dorsales Mittelhirn Syndrom, Pretektales Syndrom
ICD-10
H49.8

Parinaud syndrome refers to the occurrence of vertical gaze palsy and other neurological deficits due to damage to the cranial nerve nuclei in the region of the Mesencephalon

Symptoms

The exact neurological symptoms that may accompany Parinaud syndrome vary; however, the following symptoms are generally considered part of Parinaud syndrome[^1]:

  • Supranuclear upward gaze palsy. Horizontal eye movements are not affected.

  • Lid retraction

  • Paralysis of accommodation

  • Convergence palsy

Sylvian aqueduct syndrome

Sylvian aqueduct syndrome is a special form of Parinaud syndrome in which downward gaze palsy is additionally present[^1].

Etiology

Parinaud syndrome may occur, for example, in patients with a symptomatic Pineal cyst[^2].

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