Metronidazole is an antibiotic suitable for the treatment of infections in which the involvement of anaerobic bacteria has been demonstrated or is suspected. Systemic administration of metronidazole leads to effective concentrations in the cerebrospinal fluid1 2 as well as in brain abscesses3.
References
Koch, A., P. Federspil, and G. Hartmetz. "Metronidazole pharmacokinetics in perilymph, aqueous humor, and cerebrospinal fluid." Laryngologie, Rhinologie, Otologie und ihre Grenzgebiete 64.12 (1985): 649-651. ↩ ↩
Daschner, Franz. "Diffusion of antibiotics into the cerebrospinal fluid and brain abscesses." Antibiotika am Krankenbett. Springer, Berlin, Heidelberg, 2000. 228-229. ↩ ↩ ↩ ↩