During an infusion test, a cerebrospinal fluid substitute is administered intrathecally by infusion through a lumbar puncture under slight pressure intrathecally. Extensive measurements are performed, and pressure values are recorded continuously and subsequently analyzed.
CSF Outflow Resistance (rCSF, Rout</sub>)
One of the parameters obtained in this way is the CSF outflow resistance. It is calculated as follows1:
Rout</sub> = ( ICPend</sub> - ICPbas</sub> ) / Vinf</sub>
ICPend</sub> is defined as the highest ICP level during the infusion test. ICPbas</sub> is defined as the baseline ICP value before the start of the infusion, and Vinf</sub> is the infusion rate.
Figure
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