CISS sequence (MRI)

Synonyms
Constructive interference in steady state sequence

The CISS (Constructive interference in steady state) sequence is a gradient-echo MRI sequence that offers the advantages of a high signal-to-noise ratio, a high contrast-to-noise ratio, and intrinsic insensitivity to motion[^1].

Applications

The image contrast in a CISS sequence is determined by the T2\/T1 tissue ratio, thus providing excellent contrast between Cerebrospinal fluid and other structures in intracranial imaging. Due to this property, the CISS sequence is used to visualize structures surrounded by cerebrospinal fluid[^1].

Imaging

MRI CISS sequence
Axial MRI CISS sequence showing the cerebellopontine angle.
Aqueductal stenosis on sagittal MRI
Visualization of aqueductal stenosis on an MRI CISS sequence.
Pineal cyst on MRI, CISS sequence
Sagittal CISS MRI sequence of a patient with a pineal cyst.

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