The Zabramski classification was published by Zabramski et al. in 1994[^1] and is used for the neuroradiological classification of Cavernomas.
Classification
Zabramski Type | MRI Gradient-Echo Signal | Pathological Characteristics | ||
Type I | Hyperintense core | Hyperintense or hypointense core with a hypointense rim | - | Subacute hemorrhage surrounded by a rim containing hemosiderin, macrophages, and gliotic brain. |
Type II | Reticular mixed core | Reticular mixed core with a hypointense rim | - | Areas of hemorrhage and thrombosis of different ages surrounded by hemosiderin and gliotic brain. Calcifications may be present in some areas. |
Type III | Isointense or hypointense | Hypointense with a hypointense rim that enlarges the lesion. | Hypointense but larger than on the T2 sequence. | Chronic blood with hemosiderin within and around the hemorrhage. |
Type IV | Not visible or barely visible | Not visible or barely visible | Punctate hypointense lesions. | Two lesions in this category were documented as telangiectasias in the original study. |
