SWITCH Trial

The SWITCH trial was published in The Lancet in 2024 and investigated conservative treatment versus decompressive hemicraniectomy for deep-seated intracerebral hemorrhages[^1].

Results

Switch Trial Results
Original Figure 2 showing the results of the Switch trial. Figure adapted from Beck et al. (2024), The Lancet.

Authors' interpretation

SWITCH provides weak evidence that decompressive craniectomy plus best medical treatment might be superior to best medical treatment alone in people with severe deep intracerebral haemorrhage. The results do not apply to intracerebral haemorrhage in other locations, and survival is associated with severe disability in both groups.

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Edit · Alaric Steinmetz · (+9 −7)
  • Text added: “Authors' interpretation”
  • Text changed: “The SWITCH trial was published in The Lancet in 2024 and investigated conservative treatment versus a decompressive hemicraniectomy for deep-seated intracerebral hemorrhages [^1].”“The SWITCH trial was published in The Lancet in 2024 and investigated conservative treatment versus decompressive hemicraniectomy for deep-seated intracerebral hemorrhages [^1].”
  • Citation added: “Beck, Jürgen, et al. "Decompressive craniectomy plus best medical treatment versus best medical treatment alone for spontaneous severe deep supratentorial intracerebral haemorrhage: a randomised controlled clinical trial." The lancet 403.10442 (2024): 2395-2404.”

Article created on · Alaric Steinmetz

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