DECIMAL Trial

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The DECIMAL Trial (DEcompressive Craniectomy In MALignant MCA Infarction) was published in 2007[^1]. The study showed that early decompressive hemicraniectomy in patients with a malignant middle cerebral artery infarction significantly reduces mortality compared with the conservative treatment group.

DECIMAL Trial Profile
Overview of the study profile of the DECIMAL Trial. Figure adapted from the original publication.
DECIMAL Trial Results
Results of the DECIMAL Trial. Figure adapted from the original publication.

Authors' conclusion

In this trial, early decompressive craniectomy increased by more than half the number of patients with moderate disability and very significantly reduced (by more than half) the mortality rate compared with that after medical therapy.[^1]

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  • Text changed: “The DECIMAL Trial ( DE compressive C raniectomy I n MAL ignant MCA Infarction) was published in 2007[^1]. The study demonstrated that early decompressive hemicraniectomy in patients with a malignant middle cerebral artery infarction significantly reduces mortality compared with the conservative treatment group.”“The DECIMAL Trial ( DE compressive C raniectomy I n MAL ignant MCA Infarction) was published in 2007[^1]. The study showed that early decompressive hemicraniectomy in patients with a malignant middle cerebral artery infarction significantly reduces mortality compared with the conservative treatment group.”

Article created on · Alaric Steinmetz

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