Tumor-treating fields (TTFields) are an additional treatment option for brain tumors, such as in patients with glioblastoma. This is a noninvasive therapy in which alternating electric fields with specific frequencies and intensities are applied with the aim of preventing tumor cell division. Tumor-treating fields are intended to deactivate proteins that are critical for the cell cycle, leading to mitotic arrest followed by cellular apoptosis¹. Tumor-treating fields are applied continuously via transducer arrays, which are attached to the patient's shaved scalp².

References

Mun, Elijah J., et al. "Tumor-treating fields: a fourth modality in cancer treatment." Clinical cancer research 24.2 (2018): 266-275. ↩ ↩
Hottinger, Andreas F., Patricia Pacheco, and Roger Stupp. "Tumor treating fields: a novel treatment modality and its use in brain tumors." Neuro-oncology 18.10 (2016): 1338-1349. ↩ ↩

Tumor-treating fields (TTFields)

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