Osteosarcomas are the most common malignant primary bone tumors and are characterized by osteoid or immature bone production by malignant spindle cells1. Osteosarcomas primarily occur in the long bones of children and adolescents.
Epidemiology
Osteosarcomas occur with an incidence of approximately 1:100000 per year2. 6-10% of all osteosarcomas occur in the head and neck region3 4. Osteosarcomas in the head and neck region generally occur 10-15 years later than those in the long bones5.
Spinal Osteosarcomas
Spinal osteosarcomas typically occur in the lumbosacral region in male patients in the fourth decade of life. The prognosis for spinal osteosarcomas is poor, with a median survival of 10 months6
Imaging
References
Chennupati, Sri Kiran, et al. "Osteosarcoma of the skull base: case report and review of literature." International journal of pediatric otorhinolaryngology 72.1 (2008): 115-119. ↩ ↩ ↩ ↩
Junior, Ademar Takahama, et al. "Clinicopathological and immunohistochemical analysis of twenty-five head and neck osteosarcomas." Oral oncology 39.5 (2003): 521-530. ↩ ↩ ↩ ↩
Gadwal, Shyam R., et al. "Primary osteosarcoma of the head and neck in pediatric patients: a clinicopathologic study of 22 cases with a review of the literature." Cancer 91.3 (2001): 598-605. ↩ ↩
Shives TC, Dahlin DC, Sim FH, et al. Osteosarcoma of the spine. J Bone Joint Surg Am. 1986;68:660-668. ↩ ↩