Neuropathic pain

Neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory system[^1].

Epidemiology

The prevalence of chronic pain with neuropathic characteristics is estimated at 7-10 %[^1].

Pain characteristics

Neuropathic pain is characterized by electric shock-like or burning pain, or by painful sensations in response to nonpainful stimuli[^1].

Treatment

Pharmacological treatment

Neuropathic pain generally does not respond to opioid analgesics or conventional painkillers. However, pain relief can often be achieved with anticonvulsant medications, such as carbamazepine, clonazepam, valproic acid, or gabapentin. Tricyclic antidepressants also have a positive effect on pain intensity[^2].

Surgical treatment

In cases of therapy-refractory neuropathic pain, neuromodulatory treatments such as Spinal cord stimulators may be considered[^2].

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