Middle cerebral artery (MCA)

Synonyms
MCA, middle cerebral artery

The middle cerebral artery is a terminal branch of the Arteria carotis interna, one of the three major vessels supplying the brain arterially.

Anatomy

The middle cerebral artery is divided microsurgically into four segments[^1]:

Segment

Course

Arterial branches

Sphenoidal segment (M1)

The M1 segment courses laterally from the origin of the MCA to the genu, where the MCA forms a 90° loop. The M1 segment is divided into a pre-bifurcation segment and a post-bifurcation segment. In 86 % of cerebral hemispheres, the bifurcation is proximal to the genu of the MCA.

Origin of small cortical arterial branches: "Early branches"

Insular segment (M2)

The M2 segment of the MCA courses from the genu to the Sulcus circularis insulae.

Multiple branches, particularly at the anterior part of the Insula.

Opercular segment (M3)

The M3 segment of the MCA courses from the circular sulcus of the insula to the surface of the Sylvian fissure.

Multiple branches.

Cortical segment (M4)

The branches of the M4 segment of the MCA course from the surface of the Sylvian fissure and distribute over the cortex of the hemispheres.

Multiple branches.

Imaging

MCA Segments on DSA
Visualization of the four segments of the middle cerebral artery (MCA) on digital subtraction angiography.

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