Complex Regional Pain Syndrome (CRPS)

Last edit by Alaric Steinmetz on

Synonyms: CRPS

Complex Regional Pain Syndrome (CRPS) is a chronic pain syndrome characterized by continuously disabling burning pain. The pain is usually continuous or spontaneous, and hyperpathia and allodynia that are disproportionate to the stimulus are typical of CRPS. The underlying pathophysiology is unknown, and treatment options are limited. CRPS is divided into two different types:

CRPS Type I

CRPS Type I is nonspecific soft-tissue pain without a known nerve injury.

CRPS Type II

CRPS Type II develops as a result of a nerve injury.

Neurosurgical Treatment Options

A randomized study of Spinal Cord Stimulation (SCS) demonstrated a positive effect in CRPS Type I1, which was no longer significant at the 5-year follow-up[2].

References



    1. Kemler MA, Barendse GA, van Kleef M, et al. Spinal cord stimulation in patients with chronic reflex sympathetic dystrophy. N Engl J Med. 2000;343:618-624.  

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