Cerebral vasospasm

Synonyms
Vasospasm

Cerebral vasospasm is a pathological vascular contraction that leads to hypoperfusion of the brain parenchyma. Vasospasms can have various causes, but in neurosurgery they are particularly often observed as a complication during the course of a Subarachnoid hemorrhage.

Epidemiology

Cerebral vasospasm is a common complication in patients with aneurysmal subarachnoid hemorrhage, with an incidence of 50-90 % in this patient population[^2].

Imaging

The gold standard for visualizing vasospasms is digital subtraction angiography.

Angiography showing vasospasm
Vasospasm of the internal carotid artery on angiography.
Vasospasm in the posterior circulation
Digital subtraction angiography via the left vertebral artery showing severe vasospasm in the posterior circulation.
Vasospasm of the P1 segment on DSA
Severe vasospasm in both P1 segments of the posterior cerebral arteries on digital subtraction angiography.

Pathophysiology

Cerebral vasospasms arise from contraction of the vascular smooth muscle. The exact pathophysiological mechanism is unknown; however, it is assumed that hemoglobin released from the subarachnoid hemorrhage promotes calcium influx into the muscle cells and triggers muscle contraction[^1].

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