Cerebellothalamic tract

Synonyms
cerebellothalamische Projektion, cerebellothalamic tract, CTT

The cerebellothalamic tract (CTT) is the largest efferent pathway of the cerebellum. Its fibers originate predominantly in the Nucleus dentatusthalamus.

Anatomy

The fibers of the cerebellothalamic tract pass through the superior cerebellar peduncle. The main component of the cerebellothalamic tract is the dentatothalamic tract, which originates from the dentate nucleus, the largest nuclear region of the cerebellum.

Clinical relevance

Lesions of the cerebellothalamic tract have been described in the literature for the treatment of tremor[^1].

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Edit · Alaric Steinmetz ·
  • Citation added: “Schreglmann, Sebastian R., et al. "Unilateral cerebellothalamic tract ablation in essential tremor by MRI-guided focused ultrasound." Neurology 88.14 (2017): 1329-1333.”
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