Die Ergebnisse der DESTINY Trial wurden im Jahr 2007 veröffentlicht1. Die Studie konnte die signifikant reduzierte Mortalität bei einer dekompressiven Hemikraniektomie bei einem malignen Mediainfarkt zeigen.
Konklusion der Autoren
DESTINY showed that hemicraniectomy reduces mortality in large hemispheric stroke. With 32 patients included, the primary end point failed to demonstrate statistical superiority of hemicraniectomy, and the projected sample size was calculated to 188 patients. Despite this failure to meet the primary end point, the steering committee decided to terminate the trial in light of the results of the joint analysis of the 3 European hemicraniectomy trials.2
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